2025: The 17 Best Supplements To Reduce Alcohol Cravings

Some supplements may reduce alcohol cravings, while others can support your health as you recover from alcohol addiction.

When you are trying to quit or stay away from alcohol, cravings can be overwhelming. It is normal to seek remedies like over-the-counter herbs, vitamins and supplements to stop the cravings and support your sobriety. However, while some studies support using certain supplements, it is important to know that not all directly impact alcohol withdrawal symptoms. 

1. Vitamin B

B-vitamin deficiencies are common in those who struggle with alcohol. Although many different B vitamins can be impacted by drinking, one of the most dangerous B-vitamin deficiencies is thiamine or vitamin B1. Lack of vitamin B1 can cause a life-threatening condition called Wernicke-Korsakoff syndrome. For this reason, those who struggle with alcohol are often told to take vitamin B1. 

Although there is little data about the benefit of vitamin B1 on alcohol withdrawal cravings, supplementing with vitamin B1 is important to avoid complications from alcohol use.

2. D-Phenylalanine

D-phenylalanine is an amino acid, a chemical that is the building block of proteins. It can be found in foods like:

• Meats including beef, chicken and pork
• Tofu
• Fish
• Beans
• Milk
• Nuts
• Seeds
• Pasta
• Whole grains
• Vegetables 

Some studies have been done on d-phenylalanine, finding it improves alcohol withdrawal symptoms. However, how the amino acid fights these symptoms is unclear.

3. L-Glutamine 

L-glutamine is a natural chemical made by the body. It is also available as a nutritional supplement and found in many foods, including:

• Wheat
• Barley
• Corn
• Peanuts
• Soybeans
• Eggs
• Milk

L-glutamine can help during alcohol withdrawal by improving symptoms like nausea, vomiting and diarrhea that can occur during the detox process. Experts think it might work by protecting the gut by preventing gut permeability from deteriorating. 

4. Kudzu Extract

Kudzu is a plant in traditional medicine whose flowers and roots are used to treat conditions like alcoholism. Experts believe its activity as an isoflavonoid, plant-based estrogen or phytoestrogen might be responsible for its effects. 

Kudzu might be helpful for those who struggle with alcohol because some data show that it can help reduce alcohol intake, even in those who drink heavily. Further, kudzu does not affect sleep cycles and may start working after a single dose.

5. Milk Thistle

Milk thistle is an herb related to daisies and ragweed that is sometimes used to treat liver damage, including alcoholic liver disease. Experts think it might work by protecting the liver and lowering specific proteins like collagen produced by the body. That said, little information is available about its use during alcohol withdrawal.

6. Ashwagandha

Ashwagandha is a traditional herb used in Ayurvedic Indian medicine. It can be used to reduce fatigue, stress and anxiety, which may occur during alcohol withdrawal. Experts believe its calming effects might be due to its activity on gamma-aminobutyric acid (GABA) receptors in the brain, which slow down the central nervous system. 

One animal study showed that ashwagandha helps control mood changes, anxiety and seizures from alcohol withdrawal, but this effect has not yet been studied in humans.

7. Vitamin C

Vitamin C is an antioxidant that protects cells by preventing damage from free radicals that would otherwise harm them. Your body is unable to make vitamin C on its own, meaning that you need to obtain it from supplements or foods like:

• Oranges (and orange juice)
• Vegetables
• Melons
• Berries

Vitamin C is often used to try to protect the immune system. Because alcohol is an immunosuppressant, some people take vitamin C to combat some health risks of alcohol use. However, there is little support in clinical studies for using vitamin C for this reason.

8 Magnesium

Magnesium is a mineral involved in many different processes in the human body, ranging from DNA formation to controlling blood pressure. Magnesium is available in supplements, over-the-counter heartburn medications, and foods like:

• Dark green leafy vegetables
• Whole grains
• Nuts
• Legumes
• Fruits
• Fish

Unfortunately, magnesium deficiency is common in those who struggle with alcohol. For this reason, people who drink heavily may benefit from magnesium supplements. In addition, magnesium may help treat depression, fatigue and stomach upset, which are common symptoms of alcohol withdrawal. Magnesium may also aid in resetting some of the overly active glutamate-based brain pathways that cause alcohol withdrawal symptoms.

9. Zinc

Zinc is a mineral your body needs to perform many functions, including supporting the immune system. Zinc is also required to form an enzyme called alcohol dehydrogenase, which breaks down alcohol in your body. Zinc is available as a supplement and in foods like:

• Meats
• Fish
• Poultry
• Legumes
• Whole grains

Because those who struggle with alcohol often have nutritional deficiencies, a zinc deficiency is possible, and supplementation can be helpful. Zinc may also help reset some of the glutamate brain pathways that are overly active during alcohol withdrawal, thus possibly helping alcohol withdrawal symptoms.

10. Selenium

Selenium is a mineral that has many uses in the body, including promoting immune function. It is available as a supplement and in foods like:

• Seafood
• Meat
• Poultry
• Grains
• Nuts

Selenium deficiency is common in those who struggle with alcohol, especially if they have liver disease. Limited information is available about whether selenium is helpful in those who struggle with alcohol or during alcohol withdrawal. However, because it supports the immune system and alcohol suppresses it, some people may take supplements with selenium for its immune-boosting properties.

11. N-Acetyl Cysteine (NAC)

N-Acetyl Cysteine (NAC) is a derivative of the amino acid L-cysteine. It’s well-known for its antioxidant properties and its role in supporting the body’s production of glutathione—a vital antioxidant that helps protect cells from oxidative stress.

NAC appears to help regulate the neurotransmitter glutamate, which plays a role in reward-seeking behaviors, including cravings. By modulating glutamate levels in the brain, NAC may help reduce the intensity of cravings for alcohol.

Chronic alcohol use can deplete the body’s antioxidant systems. NAC’s ability to replenish glutathione may support better overall health, which can, in turn, stabilize mood and reduce the tendency to crave alcohol.

12. GABA

Gamma-Aminobutyric Acid (GABA) is a neurotransmitter that helps the brain maintain a calm and balanced state by inhibiting excessive neural activity.

Stress and anxiety are often triggers for alcohol cravings. As an inhibitory neurotransmitter, GABA can promote relaxation, reduce feelings of anxiety, and contribute to better sleep.

13. Passionflower

Passionflower (Passiflora incarnata) is an herb traditionally used to promote relaxation and calm. It’s been studied for its potential anxiolytic (anti-anxiety) effects.

By helping to reduce feelings of stress and anxiety, passionflower may indirectly help curb alcohol cravings triggered by emotional distress.

Some preliminary research also suggests that it can help ease mild withdrawal symptoms, particularly anxiety and agitation.

14. Chromium

Chromium is a trace mineral that helps regulate blood sugar and insulin. It is commonly found in foods like broccoli, whole grains, and lean meats.

Unstable blood sugar levels can trigger cravings, including cravings for alcohol. By helping the body maintain stable blood sugar, chromium may reduce the urge to drink when blood sugar dips.

Some evidence suggests chromium may also help with mild mood imbalances, which can reduce the desire to self-medicate with alcohol.

Avoid exceeding recommended doses of chromium to prevent potential side effects such as stomach upset or changes in insulin sensitivity.

15. Melatonin

Melatonin is a hormone produced by the pineal gland that helps regulate the sleep-wake cycle.

Poor sleep can escalate stress and anxiety, which, in turn, might worsen alcohol cravings. Supplementing with melatonin may improve sleep quality and duration.

Restless nights often lead to increased substance cravings. By promoting more consistent sleep, melatonin can indirectly help curb late-night urges to drink.

Stick to low dosages initially (often 1-3 mg) to see how your body responds. Prolonged use or high doses of melatonin can lead to grogginess or changes in sleep patterns. Consult a healthcare professional for personalized advice.

16. Valerian Root

Valerian root is an herbal supplement commonly used to help with insomnia and anxiety. It has a long history of traditional use in Europe.

Valerian root is known for its ability to promote relaxation and sleep, which can alleviate stress-related cravings for alcohol. Reduced anxiety often goes hand in hand with fewer cravings. Some people report vivid dreams or grogginess, so start with a low dose to gauge tolerance.

17. L-Theanine

L-Theanine is an amino acid found primarily in green tea leaves. It is known for its calming yet non-drowsy effects.

L-theanine can promote alpha brain wave activity, contributing to a relaxed but alert mental state. Reduced stress and improved calmness can help mitigate the desire to turn to alcohol.

By balancing neurotransmitters like GABA, dopamine, and serotonin, L-theanine may support overall mood stability.

Nutritional Deficiencies Caused by Alcohol

Nutritional deficiencies are common in those who struggle with alcohol. This is due to several reasons, including:

• Poor dietary intake in those who drink excessively. For example, someone who gets most of their calories from alcohol may eat little or choose unhealthy foods with few nutrients.
• Alcohol interferes with the absorption of many different nutrients. For example, alcohol intake interferes with digestive enzymes from the pancreas.
• Nutrient deficiencies from alcohol can predispose you to develop further deficiencies in a vicious cycle. For example, folate deficiency changes your cell linings, further predisposing you to a folate deficiency.
• Complications from alcohol use can indirectly cause nutrient deficiencies. For example, vomiting and diarrhea can cause a magnesium deficiency, while internal bleeding can cause an iron deficiency.

Although experts think many different nutrient deficiencies are common, some of the most common include:

• Vitamin A
• Vitamin C
• Vitamin D
• Vitamin E
• Vitamin K
• B vitamins
• Calcium
• Magnesium
• Iron
• Zinc

When recovering from alcohol addiction, fixing these nutrient deficiencies for your overall health is important.

Discuss Supplements With a Physician First

Before starting any new supplement, you should first discuss doing so with your doctor. This is because some supplements need to be closely monitored, including minerals like magnesium, which can build up in your body if you take too much. Further, some supplements may have drug interactions with your existing medications or can worsen other current medical conditions.

Help for Alcohol Cravings in Colorado

If you struggle with alcohol cravings, The Recovery Village at Palmer Lake can help. We offer dietitian services and nutritional counseling to help keep you healthy as you recover from alcohol. Starting from alcohol detox to cleanse your system of alcohol and continuing through rehab to help you keep sober, we are with you every step of the way. Don’t wait: contact a Recovery Advocate today to see how we can help.